Sebivo 600 mg (Tablet)
Unit Price: ৳ 312.50 (2 x 14: ৳ 8,750.00)
Strip Price: ৳ 4,375.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Telbivudine |
| Company | Novartis bangladesh ltd |
Title
- Sebivo Tablets
- Telbivudine Medicine
Category
- Medicine
- Antiviral
- Hepatitis B Treatment
Description
- Treatment for chronic hepatitis B in adult patients
- Inhibits hepatitis B virus (HBV) DNA polymerase
- 600 mg once daily dosage for chronic hepatitis B
- Pregnancy Category B
- Store at room temperature (15°C to 30°C)
Dimensions
- Tablet size: standard
Color Options
- White tablets
Function
- Inhibition of HBV DNA polymerase
Materials
- Telbivudine
Technical Specifications
- 600 mg once daily dosage for chronic hepatitis B
- Hepatitis B virus (HBV) DNA polymerase inhibitor
Design Elements
- Synthetic thymidine nucleoside analogue
Usability Features
- Oral administration
Dosage & Administration
- 600 mg once daily dosage for chronic hepatitis B
- Telbivudine Oral Solution (30 mL) available for patients who have difficulty with swallowing tablets
Indications
- Treatment of chronic hepatitis B in adult patients with viral replication and liver disease
- Initiation criteria for HBeAg-positive and HBeAg-negative patients
- On-treatment response guiding continued therapy
Pharmacology
- Synthetic thymidine nucleoside analogue with activity against hepatitis B virus (HBV)
Interaction
- Altered plasma concentration with drugs affecting renal function
- Increased risk of myopathy with specific drugs
Contraindications
- Hypersensitivity
- Combination with pegylated interferon alfa-2a
Side Effects
- Cough
- Dizziness
- Fatigue
- GI effects
- Rash
- Arthralgia
- Myalgia
- Myopathy
- Malaise
- Back pain
- Nasopharyngitis
- Headache
- Flu-like symptoms
- Insomnia
- Increased serum amylase levels
- Peripheral neuropathy
- Rhabdomyolysis
Pregnancy & Lactation
- Pregnancy Category B
- No adverse effects on developing embryos and fetuses in preclinical studies
- Crosses the placenta but no harm to the fetus at doses up to 1000 mg per kg per day in animal studies
Precautions & Warnings
- Severe acute exacerbations of hepatitis B
- Monitoring hepatic function upon discontinuation of therapy
- Lactic acidosis
- Increased risk of peripheral neuropathy when combined with pegylated interferon α-2a
- Decompensated cirrhosis
- Renal impairment
- May impair the ability to drive or operate machinery
Therapeutic Class
- Hepatic viral infections (Hepatitis B)
Storage Conditions
- Store in the original bottle at room temperature (15°C to 30°C)