Proxivir 300 mg (Tablet)
Unit Price: ৳ 85.26 (2 x 6: ৳ 1,023.12)
Strip Price: ৳ 511.56
Medicine Details
Category | Details |
---|---|
Generic | Tenofovir disoproxil |
Company | Square pharmaceuticals plc |
Indications
- Treatment of HIV-1 infection
- Treatment of chronic hepatitis B in adults
Pharmacology
- Mechanism of action: Inhibition of HIV reverse transcriptase
- Pharmacokinetics: Water soluble diester prodrug, oral bioavailability, serum concentrations, protein binding, half life
Dosage & Administration
- Adjustable dosage based on individual patient
- Oral administration once daily
- Recommended doses for adults and pediatric patients
Interaction
- Cautious coadministration with didanosine, atazanavir, lopinavir, or ritonavir
Contraindications
- Broken bone
- Enlarged fatty liver
- Severe liver disease
- Acute kidney disease
- Low phosphorus levels in blood
- High blood acidity
- Overweight
- Breastfeeding
Side Effects
- Headache
- Diarrhea
- Nausea
- Weakness
- Indigestion
- Heartburn
- Chest pain
- Drowsiness
- High cholesterol
- Kidney problems
- Depression
- Anxiety
Pregnancy & Lactation
- Pregnancy category B
- Advisory against breastfeeding
- Pediatric use
Precautions & Warnings
- Lactic acidosis/severe hepatomegaly with steatosis
- Exacerbation of hepatitis after discontinuation
- Renal impairment
- Coadministration with specific products
- HIV and HBV coinfection
- Fat redistribution
- Immune Reconstitution/Redistribution Syndrome
Use in Special Populations
- Dose adjustment for renal impairment in adults
Therapeutic Class
- Drugs for HIV / Anti-retroviral drugs
- Hepatic viral infections (Hepatitis B)
Storage Conditions
- Temperature limit
- Cool and dry storage
- Protection from light
- Child-resistant storage