Proxivir 300 mg (Tablet)

Unit Price: ৳ 85.26 (2 x 6: ৳ 1,023.12)
Strip Price: ৳ 511.56

Medicine Details

Indications

  • Treatment of HIV-1 infection
  • Treatment of chronic hepatitis B in adults

Pharmacology

  • Mechanism of action: Inhibition of HIV reverse transcriptase
  • Pharmacokinetics: Water soluble diester prodrug, oral bioavailability, serum concentrations, protein binding, half life

Dosage & Administration

  • Adjustable dosage based on individual patient
  • Oral administration once daily
  • Recommended doses for adults and pediatric patients

Interaction

  • Cautious coadministration with didanosine, atazanavir, lopinavir, or ritonavir

Contraindications

  • Broken bone
  • Enlarged fatty liver
  • Severe liver disease
  • Acute kidney disease
  • Low phosphorus levels in blood
  • High blood acidity
  • Overweight
  • Breastfeeding

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Weakness
  • Indigestion
  • Heartburn
  • Chest pain
  • Drowsiness
  • High cholesterol
  • Kidney problems
  • Depression
  • Anxiety

Pregnancy & Lactation

  • Pregnancy category B
  • Advisory against breastfeeding
  • Pediatric use

Precautions & Warnings

  • Lactic acidosis/severe hepatomegaly with steatosis
  • Exacerbation of hepatitis after discontinuation
  • Renal impairment
  • Coadministration with specific products
  • HIV and HBV coinfection
  • Fat redistribution
  • Immune Reconstitution/Redistribution Syndrome

Use in Special Populations

  • Dose adjustment for renal impairment in adults

Therapeutic Class

  • Drugs for HIV / Anti-retroviral drugs
  • Hepatic viral infections (Hepatitis B)

Storage Conditions

  • Temperature limit
  • Cool and dry storage
  • Protection from light
  • Child-resistant storage

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