Pegin 180 mcg/0.5 ml (SC Injection)
0.5 ml pre-filled syringe: ৳ 9,800.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Peginterferon alfa 2a pegylated interferon alfa 2a |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Chronic Hepatitis C
- Chronic Hepatitis B
- Compensated liver disease
- Viral replication
- Liver inflammation
Pharmacology
- Peginterferon alfa-2a
- Polyethylene glycol (PEG)
- Antiviral activity
- Antiproliferative activity
- Immune-regulating activity
Dosage & Administration
- 180 mcg dose
- Subcutaneous administration
- Abdomen injection
- Thigh injection
- 48-week treatment
Interaction
- CYP1A2 metabolized drugs
- Methadone
- Nucleoside analogues
- Zidovudine
- Azathioprine
Contraindications
- Hypersensitivity to components
- Autoimmune hepatitis
- Hepatic decompensation
- Neonate or infants
Side Effects
- Depression
- Suicidal thoughts
- Bacterial infection
- Flu-like symptoms
- Nausea/Vomiting
- Musculoskeletal pain
- Neurological effects
- Hair loss
- Hypothyroidism
Pregnancy & Lactation
- Category C for pregnancy
- Teratogenic effects
- Use effective contraception
- Excretion in human milk
- Adverse reactions in nursing infants
Precautions & Warnings
- Failed alpha interferon treatment
- Organ transplant recipients
- HIV coinfected patients
- Severe anemia risk
Use in Special Populations
- Hepatic Impairment
- Dose modifications
- Renal Impairment
- Monitor for toxicity
Overdose Effects
- Limited experiences of overdose
- No serious reactions attributed to overdose
- No specific antidote
- Dialysis not effective
Therapeutic Class
- Hepatic viral infections
Storage Conditions
- Refrigerator storage
- Temperature: 2-8°C
- Protect from light