Griseofulvin FP 500 mg (Tablet)
Unit Price: ৳ 5.00 (100's pack: ৳ 500.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Griseofulvin microsize |
| Company | Bristol pharmaceuticals ltd |
Indications
- Tinea capitis (ringworm of the scalp)
- Tinea corporis (ringworm of the body)
- Tinea pedis (athlete's foot)
- Tinea unguium (onychomycosis; ringworm of the nails)
- Tinea cruris (ringworm of the thigh)
- Tinea barbae (barber's itch)
Fungi Inhibition
- Trichophyton rubrum
- Trichophyton tonsurans
- Trichophyton mentagrophytes
- Trichophyton interdigitalis
- Trichophyton verrucosum
- Trichophyton sulphureum
- Trichophyton schoenleini
- Microsporum audouini
- Microsporum canis
- Microsporum gypseum
- Epidermophyton floccosum
- Trichophyton megnini
- Trichophyton gallinae
- Trichophyton crateriform
Mechanism of Action
- Inhibition of fungal cell mitosis
- Inhibition of nuclear acid synthesis
- Binding to spindle and cytoplasmic microtubules
- Binding to alpha and beta tubulin
- Binding to keratin in human cells
Dosage
- Accurate diagnosis of infecting organism required
- Medication must be continued until organism eradicated
- Different treatment periods for different infections
- Hygiene measures for infection control
- Dosage for adults and children
Administration
- Take with food
- Take immediately after meals
Interaction
- Dosage adjustment with warfarin-type anticoagulants
- Depression of activity with concomitant barbiturates
- Reduced efficacy of oral contraceptives
Contraindications
- Contraindicated in porphyria
- Contraindicated in hepatocellular failure
- Contraindicated in hypersensitivity to griseofulvin
- Contraindicated in pregnancy
Side Effects
- Hypersensitivity reactions
- Skin rashes
- Urticaria
- Angioneurotic edema
- Paresthesias
- Oral thrush
- Nausea
- Vomiting
- Headache
- Fatigue
- Leukopenia
- Proteinuria
Pregnancy & Lactation
- Pregnancy category C
- Potential benefit justifying potential risk
Precautions & Warnings
- Close observation during prolonged therapy
- Monitoring of organ system function
- Possibility of cross sensitivity with penicillin
- Photosensitivity warning
- Avoid exposure to intense sunlight
Therapeutic Class
- Other Antifungal preparations
Storage Conditions
- Store between 15-30°C