Anfasil 150 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 6: ৳ 240.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Silva pharmaceuticals ltd |
| Also available as |
Title
- Anfasil - Antifungal Medicine
Categories
- Medicine
- Antifungal
- Treatment
- Healthcare
Description
- Anfasil is a triazole antifungal agent indicated for various fungal infections such as vaginal candidiasis, oropharyngeal candidiasis, tinea infections, onychomycosis, and more. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes, essential for the synthesis of ergosterol in fungal cell membrane.
DosageOptions
- 150 mg as a single dose for vaginal candidiasis
- 200 mg in 1st day followed by 100 mg daily for oropharyngeal candidiasis
- 200 mg in 1st day followed by 100 mg daily for 14-30 days for esophageal candidiasis
- 400 mg as a single dose for pityriasis versicolor
- Orally/IV infusion, 400 mg on first day then 200-400 mg daily for invasive candidal infections and cryptococcal infections
- 50-400 mg daily for prevention of fungal infections in immunocompromised patients
ModeOfAction
Potent inhibitor of fungal cytochrome P-450 dependent enzymes
Indications
- Vaginal candidiasis
- Oropharyngeal candidiasis
- Oesophageal candidiasis
- Tinea infections
- Onychomycosis
- Invasive candidal infections
- Cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
Interaction
- Interacts with warfarin, sulphonylureas, phenytoin, rifampicin, oral contraceptives, cyclosporin, cimetidine, antacids, theophylline
SideEffects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Fatulence
- Rash
- Anaphylaxis
Contraindications
Known hypersensitivity to Fluconazole or related triazole compounds
PregnancyAndLactation
Not recommended during pregnancy or in women of childbearing potential unless adequate contraception is employed
PrecautionsAndWarnings
- Abnormalities in hepatic, renal, haematological and biochemical function tests observed in some patients
- Rare occurrence of exfoliative cutaneous reactions
- Not recommended during lactation
UseInSpecialPopulations
- Elderly patients: Use normal dose if no evidence of renal impairment
- Renal impairment: Dosage intervals need modification based on creatinine clearance
OverdoseEffects
Supportive measures and symptomatic treatment recommended, forced volume diuresis may increase elimination rate, haemodialysis decreases plasma levels by approximately 50%
TherapeuticClass
Drugs for subcutaneous and mycoses
StorageConditions
Keep in a dry place away from light and heat, out of the reach of children