Candinil 50 mg (Capsule)
Unit Price: ৳ 8.00 (5 x 6: ৳ 240.00)
Strip Price: ৳ 48.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Triazole antifungal agent, inhibitor of fungal cytochrome P-450 dependent enzymes, responsible for the synthesis of ergosterol
Dosage & Administration
- Dosage varies for different indications and patient groups
- Administration via oral or IV infusion
- Dosage modification for renal impairment
- Dosage for children based on weight
- Specific dosage for elderly patients
Interaction
- Interactions with warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, and oral contraceptives
- Food, cemetidine, antacids, and total body irradiation interactions
- Impact on prothrombin time, cyclosporin levels, theophylline clearance, and endogenous steroid levels
Contraindications
Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely rash
- Rare cases of anaphylaxis
Pregnancy & Lactation
Adverse fetal effects observed in animals at high doses
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological, and biochemical function tests
- Rare cases of hepatic necrosis
- Exfoliative cutaneous reactions, Stevens Johnson Syndrome, toxic epidermal necrolysis
- Monitoring and discontinuation in case of rashes
- Not recommended during lactation
- Unlikely to impair driving or use of machinery
Use in Special Populations
- Elderly patients - dosing based on renal impairment
- Renal impairment - dosing adjustment based on creatinine clearance
- Dosing adjustment for patients on haemodialysis
Overdose Effects
Supportive measures and symptomatic treatment, possible gastric lavage, forced volume diuresis, haemodialysis
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Dry place, away from light and heat, keep out of reach of children