Defungi 50 mg (Capsule)

Unit Price: ৳ 8.06 (3 x 10: ৳ 241.80)
Strip Price: ৳ 80.60

Medicine Details

Category Details
Generic Fluconazole
Company Nipro jmi pharma ltd

Indications

  • Vaginal candidiasis
  • Oropharyngeal candidiasis
  • Oesophageal candidiasis
  • Tinea corporis
  • Tinea cruris
  • Tinea pedis
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections
  • Cryptococcal infections
  • Prevention of cryptococcal meningitis
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections

Pharmacology

Potent inhibitor of fungal cytochrome P-450 dependent enzymes

Dosage & Administration

  • Adults:
    • Various dosage for different indications
  • Children: Dosage based on weight

Interaction

  • Interaction with warfarin
  • Interaction with oral sulphonyl ureas
  • Interaction with hydrochlorothiazide
  • Interaction with phenytoin
  • Interaction with rifampicin
  • Interaction with oral contraceptives
  • Interaction with cyclosporin
  • Interaction with food, cimetidine, antacids
  • Interaction with theophylline

Contraindications

Hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Gastrointestinal symptoms
  • Rash
  • Anaphylaxis

Pregnancy & Lactation

Not recommended in pregnancy or women of childbearing potential unless adequate contraception is employed

Precautions & Warnings

  • Abnormalities of hepatic, renal, and other biochemical function tests
  • Rare exfoliative cutaneous reactions
  • Discontinue if rash develops
  • Not recommended during lactation
  • Unlikely to impair ability to drive or use machinery

Use in Special Populations

  • Elderly: Normal dose if no evidence of renal impairment
  • Renal Impairment: Dosage adjustment based on creatinine clearance

Overdose Effects

Supportive and symptomatic treatment, gastric lavage, forced volume diuresis, haemodialysis

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Dry place, away from light and heat, keep out of reach of children

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