Diflu 150 mg (Capsule)
Unit Price: ৳ 22.00 (2 x 6: ৳ 264.00)
Strip Price: ৳ 132.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Potent inhibitor of fungal cytochrome P-450 dependent enzymes responsible for the synthesis of ergosterol
Dosage & Administration
- Different dosage for various indications in adults
- Dosage for children over 1 year
- Dosage adjustments for elderly, renal impairment, and specific population like children
Interaction
- Interaction with warfarin
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with combined oral contraceptive
- Interaction with cyclosporin
- Interaction study with food, cimetidine, and antacids
- Interaction study with theophyline
Contraindications
Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal symptoms like nausea, abdominal discomfort, diarrhea, flatulence
- Rare adverse events like rash
- Rare cases of anaphylaxis
Pregnancy & Lactation
Avoid use in pregnancy or in women of childbearing potential unless adequate contraception is employed; adverse fetal effects seen only at high dose levels
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological, and biochemical function tests in some patients
- Rare occurrences of hepatic necrosis
- Rare development of severe cutaneous reactions
- Discontinue therapy if rash develops in superficial fungal infection
- Discontinue therapy if bolbous lesions or erythema multiform develop
- Not recommended for use during lactation
Use in Special Populations
- Normal dose for the elderly if no evidence of renal impairment
- Dosage adjustments for patients with renal impairment
Overdose Effects
Supportive measures and symptomatic treatment with gastric lavage if necessary; forced volume diuresis may increase elimination rate; haemodialysis decreases plasma levels by approximately 50%
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat; Keep out of the reach of children