Diflu 200 mg (Capsule)

Unit Price: ৳ 25.00 (2 x 6: ৳ 300.00)
Strip Price: ৳ 150.00

Medicine Details

Indications

  • Vaginal Candidiasis
  • Oropharyngeal Candidiasis
  • Oesophageal Candidiasis
  • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections and cryptococcal infections (including meningitis)
  • Prevention of cryptococcal meningitis
  • Prevention of fungal infections in immunocompromised patients
  • Systemic Candidiasis and Cryptococcal infection
  • Superficial Candidiasis
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Triazole antifungal agent; inhibitor of fungal cytochrome P-450 dependent enzymes

Dosage & Administration

  • Adults: varying doses for different indications
  • Child dosages based on age and weight
  • Specific dosing for elderly patients and those with renal impairment
  • Dosage adjustments for patients receiving regular dialysis

Interaction

  • Interactions with warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptives, cyclosporin, food, cemetidine, antacids, theophylline
  • Potential for drug-drug interactions with other medications

Contraindications

Hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Common side effects: gastrointestinal symptoms, nausea, abdominal discomfort, diarrhea, flatulence
  • Rare adverse events: rash, anaphylaxis

Pregnancy & Lactation

Adverse fetal effects seen in animals at high dose levels, not recommended for use in pregnancy or lactation unless adequate contraception is employed

Precautions & Warnings

  • Abnormalities in hepatic, renal, haematological and other biochemical function tests observed in some patients
  • Rare cases of hepatic necrosis
  • Rare reports of exfoliative cutaneous reactions
  • Use in lactation not recommended
  • Unlikely to impair ability to drive or use machinery

Use in Special Populations

  • Elderly: normal dose recommended if no evidence of renal impairment
  • Renal impairment: dosage adjustments based on creatinine clearance

Overdose Effects

Supportive and symptomatic treatment, gastric lavage if necessary, potential for increased elimination with forced volume diuresis or haemodialysis

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Keep in a dry place away from light and heat, out of the reach of children

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