Diflu 50 mg/5 ml (Powder for Suspension)
35 ml bottle: ৳ 78.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Potent inhibitor of cytochrome P-450 enzyme system responsible for ergosterol synthesis
Dosage & Administration
- Adult dosage for various indications
- Child dosage for Superficial Candidiasis and Systemic Candidiasis & Cryptococcal infection
- Dosage adjustments for Elderly patients and Renal Impairment
- Dosage modifications based on creatinine clearance levels
Interaction
- Potential interactions with warfarin, sulfonylureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptives, cyclosporin, theophylline
- Impact of food, cimetidine, antacids, and irradiation on absorption
- Monitoring recommendations for theophylline levels
Contraindications
- Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal symptoms
- Rare occurrence of rash
- Anaphylaxis in rare cases
Pregnancy & Lactation
- Adverse fetal effects observed in animals at high doses
- Recommendation against use in pregnancy or women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, and biochemical function tests
- Rare occurrences of hepatic necrosis
- Exfoliative cutaneous reactions
- Caution in use during lactation
- Unlikelihood of impairment in driving or machinery operation
Use in Special Populations
- Dosage adjustments for Elderly patients and Renal Impairment
- Excretion mainly via urine
- Dosage modifications based on creatinine clearance
- Recommendation for monitoring cyclosporin levels
Overdose Effects
- Supportive and symptomatic treatment
- Potential use of gastric lavage
- Elimination increase with diuresis
- Haemodialysis impact on plasma levels
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children