Diflucon 50 mg (Capsule)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Aexim pharmaceuticals ltd |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Synthesis of ergosterol inhibitor
Dosage & Administration
- Dosage for Adults
- Dosage for Child over 1 year
- Use in Specific Population
- Elderly patient dosage
- Renal Impairment dosage
- Children dosage
- Dosage interval modification for renal impairment
- Dosage recommendation for children aged 5-13 years
- Use in the elderly
Interaction
- Interaction with warfarin
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with combined oral contraceptive
- Interaction with cyclosporin
- Interaction with food, cimetidine, antacids, or following total body irradiation
- Interaction with theophylline
- Potential drug-drug interactions
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Gastrointestinal tract symptoms
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals
- Not recommended in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological and other biochemical function tests
- Hepatic necrosis in rare cases
- Exfoliative cutaneous reactions
- Use during lactation not recommended
- Unlikely impairment of driving/ use of machinery
Use in Special Populations
- Use in the elderly
- Use in renal impairment
- Excretion in the urine as unchanged drug
Overdose Effects
- Supportive measures and symptomatic treatment
- Forced volume diuresis for increased elimination rate
- Haemodialysis to decrease plasma levels by approximately 50%
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children