Flucanex 150 mg (Capsule)
Unit Price: ৳ 22.00 (1 x 6: ৳ 132.00)
Strip Price: ৳ 132.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Jenphar bangladesh ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol in fungal cell membrane
Dosage & Administration
- Recommended dosage for adults for various conditions
- Dosage for children over 1 year
- Dosage adjustments in elderly patients
- Dosage adjustments in patients with renal impairment
- Dosage intervals based on creatinine clearance levels
Interaction
- Increased prothrombin time with warfarin administration
- Prolonged serum half-life of oral sulphonyl ureas
- Increased plasma concentrations of fluconazole with hydrochlorothiazide co-administration
- Increased levels of phenytoin with fluconazole co-administration
- Effect on combined oral contraceptives
- Increased cyclosporin concentrations in renal transplant patients
Contraindications
- Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Well tolerated product
- Common gastrointestinal side effects like nausea and abdominal discomfort
- Rare occurrence of rash and anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects seen in animals only at high dose levels
- Not recommended for use in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, hematological tests observed in some patients
- Rare cases of hepatic necrosis
- Exfoliative cutaneous reactions in rare cases
- Monitoring required for severe cutaneous reactions in AIDS patients
- Discontinuation of therapy for rash development in certain conditions
Use in Special Populations
- Use in the elderly
- Dosage adjustments in renal impairment patients based on creatinine clearance levels
Overdose Effects
- Supportive measures and symptomatic treatment in case of overdosage
- Potential treatment methods like gastric lavage and haemodialysis
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children