Flucolet 50 mg/5 ml (Powder for Suspension)
35 ml bottle: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Amulet pharmaceuticals ltd |
| Also available as |
Title
- Flucolet Antifungal Medicine
Categories
- Antifungal
- Medication
- Pharmacology
- Healthcare
Description
- Flucolet is an antifungal agent used to treat various fungal infections such as vaginal candidiasis, oropharyngeal candidiasis, tinea, onychomycosis, and invasive candidal infections, as well as for the prevention of fungal infections in immunocompromised patients. It is available in various dosage forms and administration routes.
Indication
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections
- Cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
Pharmacology
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol in fungal cell membrane
Dosage administration
- Adult dosage for various infections
- Child dosage for superficial candidiasis and systemic candidiasis
- Dosage adjustments for elderly patients and renal impairment
Interaction
- Interaction with warfarin leading to increased prothrombin time
- Prolongation of serum half-life of oral sulphonylureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin and rifampicin
- Effects on combined oral contraceptives
- Increase in cyclosporin concentrations
- Absorption interactions with food, cimetidine, and antacids
- Interaction with theophylline leading to decreased plasma clearance
Contraindications
- Hypersensitivity to Fluconazole or related triazole compounds
Side effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely rash and anaphylaxis
Pregnancy lactation
- Adverse fetal effects in animals at high dose levels
- Not recommended for use in pregnancy or lactation without adequate contraception
Precautions warnings
- Abnormalities in hepatic, renal, and biochemical function tests observed in some patients
- Rare occurrences of hepatic necrosis
- Rare cases of exfoliative cutaneous reactions
- Caution in patients with underlying diseases
- Not recommended for use during lactation
- Unlikely to impair driving or use of machinery
Special populations
- Dosage adjustments for elderly patients and renal impairment
Overdose effects
- Supportive and symptomatic treatment
- Potential for gastric lavage if necessary
- Potential treatment with forced volume diuresis and haemodialysis
Therapeutic class
- Antifungal medication
Storage conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children