Fluco-S 150 mg (Capsule)
Unit Price: ৳ 22.00 (10's pack: ৳ 220.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Seema pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Triazole antifungal agent, potent inhibitor of fungal cytochrome P-450 dependent enzymes, essential component of fungal cell membrane responsible for the synthesis of ergosterol.
Dosage & Administration
- Adults: Varying dosage for different indications
- Child dosage based on weight
- Use in Specific Population - Elderly, Renal Impairment, Children
Interaction
- Fuconazole's interaction with warfarin
- Interaction with oral sulphonylureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin and rifampicin
- Interaction with combined oral contraceptive
- Interaction with cyclosporin
- Absorption interaction with food, cimetidine, antacids, and irradiation
- Interaction with theophylline
Contraindications
Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely rash
- Rarely anaphylaxis
Pregnancy & Lactation
Adverse fetal effects seen in animals only at high dose levels, not recommended for use in pregnancy or in women of childbearing potential unless using adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, hematological and biochemical function tests in some patients
- Rare cases of hepatic necrosis
- Exfoliative cutaneous reactions
- Use during lactation not recommended
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Elderly: normal dose if no evidence of renal impairment
- Renal impairment: dosage adjustment based on creatinine clearance
Overdose Effects
Supportive measures and symptomatic treatment, forced volume diuresis may increase elimination rate, haemodialysis decreases plasma levels by approximately 50%
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat, keep out of the reach of children