Flufun 150 mg (Capsule)
Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Astra biopharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis
- Tinea cruris
- Tinea pedis
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections
- Cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Potent inhibitor of fungal cell membrane synthesis
Dosage & Administration
- Different dosage for adults and children
- Single dose and multiple dose therapy
- Dosage modification for renal impairment
- Specific dosage for different indications
Interaction
- Interaction with warfarin
- Prolongation of prothrombin time
- Co-administration with oral sulphonyl ureas
- Increased plasma concentrations with hydrochlorothiazide
- Possible increase in phenytoin levels
- Effect on combined oral contraceptives
- Interaction with cyclosporin
- Effect on theophyline plasma clearance
- No impairment of absorption with food, cimetidine, or antacids
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal symptoms
- Nausea
- Abdominal discomfort
- Diarrhea
- Flatulence
- Rarely encountered rash
- Incidence of anaphylaxis is less than 1%
Pregnancy & Lactation
- Adverse fetal effects seen in animals
- Use not recommended in pregnancy or lactation
Precautions & Warnings
- Observation for abnormalities in hepatic, renal, hematological, and biochemical function
- Rare cases of hepatic necrosis
- Development of severe cutaneous reactions
- Discontinue therapy in case of rash
- Not recommended for use during lactation
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Normal dose for the elderly
- Dosage adjustment in renal impairment
Overdose Effects
- Supportive and symptomatic treatment
- Gastric lavage if necessary
- Forced volume diuresis to increase elimination rate
- Haemodialysis decreases plasma levels by approximately 50%
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children