Flugal 150 mg (Capsule)
Unit Price: ৳ 22.14 (2 x 10: ৳ 442.80)
Strip Price: ৳ 221.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections
- Cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of systemic fungal infections
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Synthesis of ergosterol inhibitor
Dosage & Administration
- Different dosage for different types of infections
- Single dose and multiple doses
- Dosage adjustment based on age and weight
- Specific dosage for children and elderly patients
- Dosage modification for patients with renal impairment
Interaction
- Interaction with warfarin and prothrombin time
- Interaction with sulphonyl ureas and hypoglycemia possibility
- Interaction with hydrochlorothiazide and plasma concentrations
- Interaction with phenytoin and rifampicin
- Interaction with combined oral contraceptives and endogenous steroid levels
- Interaction with cyclosporin and monitoring recommended
- Absorption interactions with food, cimetidine, and antacids
- Decrease in theophyline clearance and potential toxicity
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal side effects
- Rare adverse events like rash and anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals at high doses
- Not recommended for pregnant or breastfeeding women without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, and biochemical function tests
- Rare cases of hepatic necrosis
- Cutaneous reactions like Stevens Johnson Syndrome and toxic epidermal necrolysis
- Discontinuation in case of rash development
- Not recommended during lactation
- Unlikeliness to impair driving or machinery use
Use in Special Populations
- Normal dose for elderly if no renal impairment
- Dosage adjustments for renal impairment based on creatinine clearance
Overdose Effects
- Supportive measures and symptomatic treatment
- Possible gastric lavage if necessary
- Increase in elimination rate with forced volume diuresis
- Approximately 50% plasma levels decrease with haemodialysis
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children