Flugard 150 mg (Capsule)
Unit Price: ৳ 22.00 (3 x 10: ৳ 660.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Pharmasia limited |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Triazole antifungal agent, potent inhibitor of fungal cytochrome P-450 dependent enzymes, essential for the synthesis of ergosterol
Dosage & Administration
- Adults dosage
- Child over 1 year dosage
- Use in Specific Population
- Elderly patient dosage
- Renal Impairment dosage
- Children renal clearance dosage
- Dosing for children aged 5-13 years
- Dosage adjustment based on creatinine clearance
Interaction
- Interaction with warfarin
- Interaction with sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with oral contraceptive
- Interaction with cyclosporin
- Interaction with food, cemetidine, antacids
- Interaction with theophylline
- Unspecified drug-drug interactions
Contraindications
Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals at high dose levels
- Not recommended during pregnancy or in women of childbearing potential
- Use in pregnancy only with adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological and biochemical function tests in some patients
- Rare hepatic necrosis
- Exfoliative cutaneous reactions
- Rash development in superficial and invasive/systemic fungal infections
- Use in lactation
- Impact on driving/use of machinery
Use in Special Populations
- Use in the elderly
- Use in renal impairment
- Adjustments in single and multiple dose therapy based on renal function
Overdose Effects
Supportive measures, symptomatic treatment, gastric lavage if necessary, forced volume diuresis, haemodialysis
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Dry place away from light and heat, keep out of the reach of children