Fluma 50 mg (Capsule)

Unit Price: ৳ 8.00 (50's pack: ৳ 400.00)

Medicine Details

Category Details
Generic Fluconazole
Company Modern pharmaceuticals ltd
Also available as

Indications

  • Vaginal Candidiasis
  • Oropharyngeal Candidiasis
  • Oesophageal Candidiasis
  • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections and cryptococcal infections (including meningitis)
  • Prevention of cryptococcal meningitis
  • Prevention of fungal infections in immunocompromised patients
  • Systemic Candidiasis and Cryptococcal infection
  • Superficial Candidiasis
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Potent inhibitor of fungal cytochrome P-450 dependent enzymes responsible for ergosterol synthesis

Dosage & Administration

  • Adults:
    • Specific dosages for different conditions
  • Children:
    • Dosage based on weight for different conditions
  • Use in Specific Population:
    • Dosage adjustments for elderly, patients with renal impairment, and children

Interaction

  • Interaction with warfarin, oral sulphonylureas, hydrochlorothiazide, phenytoin, rifampicin, combined oral contraceptive, cyclosporin, food, cimetidine, antacids, theophylline, and other medications

Contraindications

Hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Gastrointestinal symptoms
  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Fatulence
  • Rarely encountered adverse events such as rash and anaphylaxis

Pregnancy & Lactation

Avoid use in pregnancy or in women of childbearing potential unless adequate contraception is used

Precautions & Warnings

  • Abnormalities in hepatic, renal, and biochemical function tests
  • Risk of liver enzyme rise and hepatic necrosis
  • Potential development of severe cutaneous reactions
  • Monitoring for rash and discontinuation if necessary
  • Not recommended during lactation
  • Unlikely to impair ability to drive or use machinery

Use in Special Populations

  • Elderly: Normal dose usage if no evidence of renal impairment
  • Renal Impairment: Dosage adjustments based on creatinine clearance

Overdose Effects

Supportive and symptomatic treatment, gastric lavage, and potential increase in elimination rate through forced volume diuresis or haemodialysis

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Keep in a dry place away from light and heat, out of the reach of children

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