Flumart 150 mg (Capsule)
Unit Price: ৳ 10.00 (2 x 6: ৳ 120.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Desh pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
- Synthesis of ergosterol inhibitor
Dosage & Administration
- Dosage for Vaginal Candidiasis: 150 mg as a single dose
- Dosage for Oropharyngeal Candidiasis: 200 mg in 1st day followed by 100 mg daily for 14 days
- Dosage for Oesophageal Candidiasis: 200 mg in 1st day followed by 100 mg daily for 14-30 days
- Dosage for Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea: 150 mg weekly for 4-6 weeks
- Dosage for Kerion: 50 mg daily for 20 days
- Dosage for Pityriasis versicolor: 400 mg as a single dose
- Dosage for Onychomycosis: 150 mg weekly for 12 months
- Dosage for Invasive candidal infections and cryptococcal infections (including meningitis): Orally or by IV infusion, 400 mg on first day then 200-400 mg daily
- Dosage for Prevention of cryptococcal meningitis: Orally or by IV infusion 200 mg daily
- Dosage for Prevention of fungal infections in immunocompromised patients: Orally or by IV infusion, 50-400 mg daily
- Child Dosage for Superficial Candidiasis: 1-2 mg/kg daily
- Child Dosage for Systemic Candidiasis & Cryptococcal infection: 3-6 mg/kg daily
Interaction
- Interaction with warfarin
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with combined oral contraceptives
- Interaction with cyclosporin
- Interaction with cemetidine, antacids
- Interaction with theophylline
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Fatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects seen in animals
- Not recommended in pregnancy or nursing mothers
- Use contraception in women of childbearing potential
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological tests observed
- Potential hepatic necrosis in severe cases
- Exfoliative cutaneous reactions risk
- May cause Stevens Johnson Syndrome and toxic epidermal necrolysis in rare cases
- Not recommended during lactation
- Unlikely to impair driving or machinery usage
Use in Special Populations
- Normal dose recommended for elderly without renal impairment
- Adjust dosage intervals for renal impairment