Flunol 50 mg (Capsule)
Unit Price: ৳ 8.00 (4 x 10: ৳ 320.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol
Dosage & Administration
- Adults dosages for various indications
- Child dosages for superficial and systemic candidiasis
- Dosage adjustments in elderly patients and patients with renal impairment
Interaction
- Increased prothrombin time after warfarin administration
- Prolongation of serum half-life of concomitantly administered oral sulphonylureas
- Increase in plasma concentrations of fuconazole by co-administration of hydrochlorothiazide
- Potential interaction with phenytoin and rifampicin
- Effect on combined oral contraceptives
- Slow increase in cyclosporin concentrations
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely encountered rash
- Rare cases of anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects seen only in animals at high dose levels
- Not recommended in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities of hepatic, renal, haematological, and biochemical function tests
- Rare cases of hepatic necrosis
- Development of severe cutaneous reactions in some patients
- Caution in lactating mothers
- Unlikely to impair the ability to drive or use machinery
Use in Special Populations
- Use in the elderly
- Use in renal impairment
Overdose Effects
- Supportive measures and symptomatic treatment
- Possible use of gastric lavage
- Forced volume diuresis may increase elimination rate
- Haemodialysis decreases plasma levels by approximately 50%
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children