Flunol 50 mg/5 ml (Powder for Suspension)
35 ml bottle: ৳ 78.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Potent inhibitor of fungal cell membrane synthesis of ergosterol
Dosage & Administration
- Different dosage for different indications
- Adult and Child dosage
- Dosage modification for renal impairment
- Dosage for specific populations like elderly
- Use in patients receiving regular dialysis
Interaction
- Interaction with warfarin
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with combined oral contraceptives
- Interaction with cyclosporin
- Interaction with food, cemetidine, antacids
- Interaction with theophylline
- Potential for other drug interactions
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Well tolerated but may cause gastrointestinal symptoms
- Rarely rash and anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals
- Should not be used in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological, and other biochemical function tests in some patients
- Rare exfoliative cutaneous reactions
- Discontinue in case of rash in superficial fungal infection
- Use not recommended during lactation
- Unlikely to impair driving or use of machinery
Use in Special Populations
- Normal dose for elderly with no evidence of renal impairment
- Dosage adjustment for renal impairment based on creatinine clearance
- Excretion predominantly in the urine
- Dosage adjustments for patients with renal impairment
Overdose Effects
- Supportive and symptomatic treatment
- Forced volume diuresis may increase elimination rate
- Haemodialysis may decrease plasma levels
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children