Fluzo 50 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Potent inhibitor of ergosterol synthesis
Dosage & Administration
- Dosage varies based on the indication and age group
- Recommended doses for adults and children over 1 year
- Special considerations for elderly patients and those with renal impairment
Interaction
- Potential interactions with warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptives, cyclosporin, theophylline
- Impact of food, cimetidine, antacids on absorption
- Clinically significant effects on drug levels and metabolism
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal symptoms like nausea, abdominal discomfort, diarrhea, flatulence
- Rare occurrences of rash, anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects seen in animals at high doses
- Not recommended for use in pregnancy or lactation without adequate contraception
Precautions & Warnings
- Monitoring for hepatic, renal, and hematological abnormalities
- Potential for serious cutaneous reactions in some patients
- Caution in patients receiving multiple concomitant medications
- Monitoring may be necessary in patients with underlying diseases
Use in Special Populations
- Normal dosing for the elderly if no renal impairment
- Dosage adjustments for patients with renal impairment
- Excretion mostly via urine
Overdose Effects
- Supportive and symptomatic treatment recommended
- Gastric lavage if necessary
- Forced diuresis may increase elimination rate
- Haemodialysis may decrease plasma levels by approximately 50%
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Store in a dry place away from light and heat
- Keep out of the reach of children