Fluzo 150 mg (Tablet)
Unit Price: ৳ 22.00 (1 x 10: ৳ 220.00)
Strip Price: ৳ 220.00
Medicine Details
Category | Details |
---|---|
Generic | Fluconazole |
Company | Pacific pharmaceuticals ltd |
Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Potent inhibitor of fungal cell membrane synthesis of ergosterol
Dosage & Administration
- Single dose for Vaginal Candidiasis
- Daily dose for Oropharyngeal Candidiasis
- Weekly dose for Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Daily dose for Kerion
- Single dose for Pityriasis versicolor
- Weekly dose for Onychomycosis
- Oral or IV infusion for Invasive candidal infections and cryptococcal infections
- Daily dose for Prevention of cryptococcal meningitis
- Daily dose for Prevention of fungal infections in immunocompromised patients
- Dose based on weight for Superficial Candidiasis
- Dose based on weight for Systemic Candidiasis & Cryptococcal infection
- Dose adjustments for Renal Impairment
- Use in Elderly patients
Interaction
- Interaction with warfarin
- Interaction with sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with oral contraceptives
- Interaction with cyclosporin
- Food interactions
Contraindications
- Known hypersensitivity to Fluconazole
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Fatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals
- Not recommended for use in pregnancy or lactation
Precautions & Warnings
- Abnormalities in hepatic, renal, and haematological tests
- Rare cases of hepatic necrosis
- Exfoliative cutaneous reactions
- Monitoring required for severe cutaneous reactions
- Not recommended during lactation
- No impairment on driving or machinery use
Use in Special Populations
- Use in the Elderly
- Dose adjustments in Renal Impairment
- Dosing intervals adjustment based on creatinine clearance
Overdose Effects
- Supportive and symptomatic treatment
- Gastric lavage if necessary
- Forced volume diuresis
- Haemodialysis for elimination
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place
- Keep away from light and heat
- Keep out of the reach of children