Fungard 50 mg (Capsule)
Unit Price: ৳ 8.23 (30's pack: ৳ 246.90)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Cosmic pharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Fluconazole is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes. Cytochrome P-450 enzyme system is essential component of fungal cell membrane which is responsible for the synthesis of ergosterol.
Dosage & Administration
- Dosage varies for different indications
- Dosage interval modification for renal impairment
- Recommended doses for children
- Dosage adjustment for elderly patients
Interaction
- Interaction with warfarin and prothombin time
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin and rifampicin
- Interaction with combined oral contraceptive
- Interaction with cyclosporin
- Effect of food, cemetidine, antacids on absorption
- Interaction with theophylline
Contraindications
- Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
Fluconazole should not be used in pregnancy or in women of childbearing potential unless adequate contraception is employed.
Precautions & Warnings
- Abnormalities of hepatic, renal, haematological and biochemical function
- Hepatic necrosis
- Exfoliative cutaneous reactions
- Use during lactation
- Effect on driving/use of machinery
Use in Special Populations
- Use in the elderly
- Use in renal impairment
Overdose Effects
Supportive measures and symptomatic treatment, gastric lavage if necessary, forced volume diuresis, haemodialysis
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat, Keep out of the reach of children