Fungitrol 150 mg (Capsule)
Unit Price: ৳ 22.06 (3 x 4: ৳ 264.72)
Strip Price: ৳ 88.24
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Rangs pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol in fungal cell membrane
Dosage & Administration
- Dosage instructions for various types of infections
- Special dosages for children based on weight
- Dosage adjustments for elderly patients and those with renal impairment
Interaction
- Increased prothrombin time with warfarin
- Effects on sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptives, cyclosporine
- Impact of food, cemetidine, antacids on absorption
- Potential interactions with theophylline
- Limited drug-drug interaction studies with other medications
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Well tolerated in general
- Common side effects related to gastrointestinal tract
- Rare incidence of rash and anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects seen in animals at high doses
- Not recommended for use in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, and biochemical function tests observed in some patients
- Rare cases of hepatic necrosis and severe cutaneous reactions
- Caution with use in patients with serious underlying diseases
- Avoid use during lactation
- Unlikely to impair driving or machinery use
Use in Special Populations
- Dosing considerations for the elderly and patients with renal impairment
Overdose Effects
- Supportive measures and symptomatic treatment
- Possible use of gastric lavage
- Forced volume diuresis for increased elimination rate
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Dry place away from light and heat
- Keep out of reach of children