Funzole 50 mg (Capsule)
Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Monicopharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Prevention of fungal infections in immunocompromised patients
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Fluconazole is a triazole antifungal agent, and a potent inhibitor of fungal cytochrome P-450 dependent enzymes responsible for the synthesis of ergosterol.
Dosage & Administration
- Adults:
- Different doses for various indications
- Different doses for renal impairment
- Doses for prevention of fungal infections in immunocompromised patients
- Specific doses for children
- Doses for elderly patients
- Child over 1 year dosage:
- In Superficial Candidiasis: 1-2 mg/kg daily
- In Systemic Candidiasis & Cryptococcal infection: 3-6 mg/kg daily
Interaction
- Interaction with warfarin
- Interaction with oral sulfonylureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with combined oral contraceptives
- Interaction with cyclosporine
- Interaction with food, cimetidine, antacids, or following total body irradiation
- Interaction with theophylline
Contraindications
Fluconazole should not be used in patients with known hypersensitivity to Fluconazole or related triazole compounds.
Side Effects
- Gastrointestinal symptoms
- Rarely encountered rash
- Rare cases of anaphylaxis
Pregnancy & Lactation
Fluconazole should not be used in pregnancy or in women of childbearing potential unless adequate contraception is employed.
Precautions & Warnings
- Observation of hepatic, renal, haematological, and other biochemical function tests
- Rare occurrence of exfoliative cutaneous reactions
- Discontinuation if rash develops
- Use during lactation not recommended
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Use in the elderly
- Adjustment in dosage intervals for renal impairment
Overdose Effects
In the event of overdosage, supportive measures and symptomatic treatment should be administered, and forced volume diuresis may be considered.
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.