F-Zol 200 mg (Capsule)
Unit Price: ৳ 25.00 (2 x 6: ৳ 300.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Fluconazole is a potent inhibitor of fungal cytochrome P-450 dependent enzymes and essential for fungal cell membrane synthesis.
Dosage & Administration
- Dosage varies for different indications and patient groups
- Administration includes single dose, daily doses, and weekly doses
- Dosage interval modification for patients with renal impairment
Interaction
- Interaction with warfarin and prothrombin time
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin and rifampicin
- Interaction with combined oral contraceptive
- Interaction with cyclosporin, theophyline, and food/cimetidine/antacids/radiation
- Potential for drug-drug interactions with other medications
Contraindications
Fluconazole should not be used in patients with known hypersensitivity to Fluconazole or related triazole compounds.
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely encountered adverse events such as rash and anaphylaxis
Pregnancy & Lactation
Fluconazole should not be used in pregnancy or in women of childbearing potential unless adequate contraception is employed.
Precautions & Warnings
- Observation of hepatic, renal, hematological, and biochemical function tests
- Assessment of risk-benefit ratio for patients with significant rise of liver enzymes
- Rare development of exfoliative cutaneous reactions
- Discontinuation of therapy in case of rashes in superficial or invasive/systemic fungal infections
- F-Zol found in human breast milk at concentrations similar to plasma
Use in Special Populations
- Normal dose usage in the elderly if no evidence of renal impairment
- Dosage adjustments in renal impairment based on creatinine clearance
Overdose Effects
In the event of overdosage, supportive measures and symptomatic treatment with gastric lavage if necessary may be adequate.
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.