F-Zol 200 mg/100 ml (IV Infusion)

100 ml bottle: ৳ 200.00

Medicine Details

Indications

  • Vaginal Candidiasis
  • Oropharyngeal Candidiasis
  • Oesophageal Candidiasis
  • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections and cryptococcal infections (including meningitis)
  • Prevention of cryptococcal meningitis
  • Prevention of fungal infections in immunocompromised patients
  • Systemic Candidiasis and Cryptococcal infection
  • Superficial Candidiasis
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Triazole antifungal agent

Dosage & Administration

  • Adults:
    • Various dosage for different indications such as Vaginal Candidiasis, Oropharyngeal Candidiasis, Tinea corporis, Kerion, etc.
    • Dosage modification for Elderly patients and Renal Impairment
    • Dosage for children based on weight
  • Use in Specific Population: Dosage adjustment for Elderly patients and patients with Renal Impairment

Interaction

  • Interaction with warfarin
  • Interaction with oral sulphonyl ureas
  • Interaction with hydrochlorothiazide
  • Interaction with phenytoin
  • Interaction with rifampicin
  • Interaction with combined oral contraceptives
  • Interaction with cyclosporin
  • Effect of food, cimetidine, antacids on absorption
  • Interaction with theophylline

Contraindications

Hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Flatulence
  • Rarely encountered adverse events such as rash and anaphylaxis

Pregnancy & Lactation

Adverse fetal effects seen in animals only at very high dose levels associated with maternal toxicity

Precautions & Warnings

  • Abnormalities of hepatic, renal, haematological and other biochemical function tests observed in some patients
  • Rare instances of hepatic necrosis
  • Rare development of exfoliative cutaneous reactions
  • Not recommended for use during lactation

Use in Special Populations

  • Elderly: Normal dose should be used if no evidence of renal impairment
  • Renal Impairment: Dosage adjustments based on creatinine clearance

Overdose Effects

Supportive and symptomatic treatment recommended, potential for forced volume diuresis and haemodialysis

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Keep in a dry place away from light and heat, Keep out of the reach of children

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