Lucan-R 50 mg (Capsule)
Unit Price: ৳ 8.03 (4 x 10: ৳ 321.20)
Strip Price: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Renata limited |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Fluconazole is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes responsible for the synthesis of ergosterol in the fungal cell membrane.
Dosage & Administration
- Adults dosage for different indications
- Child dosage for different indications
- Dosage adjustments for elderly patients
- Dosage adjustments for patients with renal impairment
- Dosage adjustments for patients receiving regular dialysis
Interaction
- Interaction with warfarin
- Interaction with sulphonylureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with oral contraceptives
- Interaction with cyclosporin
- Interaction with antacids
- Interaction with theophylline
Contraindications
Fluconazole should not be used in patients with known hypersensitivity to Fluconazole or related triazole compounds.
Side Effects
- Common gastrointestinal side effects
- Rare occurrence of rash
- Rare occurrence of anaphylaxis
Pregnancy & Lactation
Fluconazole should not be used in pregnancy or in women of childbearing potential unless adequate contraception is employed.
Precautions & Warnings
- Observation of hepatic, renal, and other biochemical function tests
- Assessment of risk-benefit ratio in case of liver enzyme rise
- Cutaneous reactions
- Discontinuation in case of rash during treatment
- Use not recommended during lactation
- Unlikelihood of therapy impairing ability to drive or use machinery
Use in Special Populations
- Use in the elderly
- Dosage adjustments in patients with renal impairment
Overdose Effects
Supportive and symptomatic treatment in case of overdosage. Forced volume diuresis may increase elimination rate. Haemodialysis may decrease plasma levels.
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.