Lucan-R 150 mg (Capsule)

Unit Price: ৳ 22.08 (2 x 6: ৳ 264.96)
Strip Price: ৳ 132.48

Medicine Details

Title

Lucan-R

Categories

  • Antifungal Medicine
  • Therapeutic Drugs

Description

Lucan-R is a triazole antifungal agent used for various indications such as Vaginal Candidiasis, Oropharyngeal Candidiasis, Tinea corporis, Oesophageal Candidiasis, and more. It inhibits fungal cytochrome P-450 dependent enzymes responsible for the synthesis of ergosterol in the fungal cell membrane. The dosage and administration vary based on the type of infection and patient age. It is contraindicated in patients with known hypersensitivity to fluconazole or related triazole compounds. Lucan-R may cause gastrointestinal symptoms, and precautions are advised for patients with underlying diseases like AIDS and cancer.

Attributes

  • Indications:
    • Vaginal Candidiasis
    • Oropharyngeal Candidiasis
    • Tinea corporis
    • Oesophageal Candidiasis
    • Kerion
    • Pityriasis versicolor
    • Onychomycosis
    • Invasive candidal infections
    • Cryptococcal infections
    • Prevention of cryptococcal meningitis
    • Prevention of fungal infections in immunocompromised patients
    • Systemic Candidiasis
    • Fungal urinary tract infections
    • Disseminated candidiasis
    • Prophylaxis for fungal infection in neutropenic cancer patients
    • Acute treatment of other systemic fungal infections
  • Pharmacology: Potent inhibitor of fungal cytochrome P-450 dependent enzymes essential for ergosterol synthesis
  • Dosage & Administration: Varies by infection type and patient age; requires dosage adjustment for renal impairment
  • Interaction:
    • Warfarin
    • Sulphonyl ureas
    • Hydrochlorothiazide
    • Phenytoin
    • Rifampicin
    • Oral contraceptives
    • Cyclosporin
    • Food/Cimetidine/Antacids/Total body irradiation
    • Theophylline
  • Contraindications: Known hypersensitivity to fluconazole or related triazole compounds
  • Side Effects:
    • Nausea
    • Abdominal discomfort
    • Diarrhoea
    • Fatulence
    • Rash
    • Anaphylaxis
  • Pregnancy & Lactation: Not recommended unless adequate contraception is employed
  • Precautions & Warnings: Requires assessment of risk-benefit ratio in patients with abnormal hepatic, renal or haematological function; discontinuation if rash develops in superficial or invasive/systemic fungal infections; not recommended during lactation
  • Use in Special Populations: Requires dosage adjustment for renal impairment; normal dose for elderly if no renal impairment
  • Overdose Effects: Supportive and symptomatic treatment; forced volume diuresis and hemodialysis may be adequate
  • Therapeutic Class: Drugs for subcutaneous and mycoses
  • Storage Conditions: Keep in a dry place away from light and heat; keep out of the reach of children

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