Nispore 50 mg (Capsule)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Fluconazole is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes.
Dosage & Administration
- Adults:
- Different dosage for specific conditions and duration
- Dosage modification for elderly, renal impairment, and children
- Child over 1 year:
- Different dosage for specific conditions
- Dosage based on weight
Interaction
- Interaction with warfarin
- Interaction with sulphonylureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with oral contraceptives
- Interaction with cyclosporin
- Factors affecting absorption
- Interaction with theophylline
- Potential for other drug interactions
Contraindications
Fluconazole should not be used in patients with known hypersensitivity to Fluconazole or to related triazole compounds.
Side Effects
- Gastrointestinal symptoms
- Rarely encountered adverse events like rash
- Rare cases of anaphylaxis
Pregnancy & Lactation
Avoid use in pregnancy or in women of childbearing potential unless adequate contraception is employed.
Precautions & Warnings
- Abnormalities in hepatic, renal function tests
- Rare occurrences of severe cutaneous reactions
- Discontinuation in case of rashes
- Caution in patients with serious underlying diseases such as AIDS and cancer
- Avoid use during lactation
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Use in the elderly
- Dosage adjustment in renal impairment based on creatinine clearance
Overdose Effects
Supportive measures and symptomatic treatment recommended
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.