Sacona 150 mg (Capsule)
Unit Price: ৳ 16.05 (12's pack: ৳ 192.60)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Marker pharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Potent inhibitor of fungal cytochrome P-450 dependent enzymes essential for synthesis of ergosterol
Dosage & Administration
- Adults:
- Various dosage regimens for different indications
- Specific dosage for children over 1 year
- Use in Specific Population:
- Dosage adjustment for elderly patients
- Dosage modification based on renal impairment
- Renal clearance in children may be more rapid than in adults
Interaction
- Increased prothrombin time with warfarin
- Prolonged serum half-life of oral sulphonyl ureas
- Increased plasma concentrations with hydrochlorothiazide
- Potential interactions with phenytoin, rifampicin, and cyclosporin
- Limited effect on combined oral contraceptives
- Interaction with food, cemetidine, antacids, and theophylline
Contraindications
Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal symptoms
- Rare adverse events such as rash and anaphylaxis
Pregnancy & Lactation
Not recommended for use in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities of hepatic, renal, and biochemical function tests observed in some patients
- Rare cases of severe cutaneous reactions
- Discontinue if rash develops during treatment for superficial fungal infection
- Not recommended for use during lactation
Use in Special Populations
- Elderly: Normal dosage if no evidence of renal impairment
- Renal Impairment: Dosage modification based on creatinine clearance
Overdose Effects
Supportive measures and symptomatic treatment recommended; forced volume diuresis may increase elimination rate
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat; keep out of the reach of children