Segal 50 mg (Capsule)

Unit Price: ৳ 8.00 (20's pack: ৳ 160.00)

Medicine Details

Indications

  • Vaginal Candidiasis
  • Oropharyngeal Candidiasis
  • Oesophageal Candidiasis
  • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections and cryptococcal infections (including meningitis)
  • Prevention of cryptococcal meningitis
  • Prevention of fungal infections in immunocompromised patients
  • Systemic Candidiasis and Cryptococcal infection
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Fluconazole is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes and responsible for the synthesis of ergosterol.

Dosage & Administration

Includes adult dosage for various conditions, child dosage, use in specific populations like elderly patients, renal impairment, and precautions.

Interactions

  • Warfarin
  • Oral sulphonyl ureas
  • Hydrochlorothiazide
  • Phenytoin
  • Rifampicin
  • Combined oral contraceptive
  • Cyclosporin
  • Food, cimetidine, antacids
  • Theophyline

Contraindications

Should not be used in patients with known hypersensitivity to Fluconazole or related triazole compounds.

Side Effects

  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Flatulence
  • Rash
  • Anaphylaxis

Pregnancy & Lactation

Should not be used in pregnancy or in women of child bearing potential unless adequate contraception is employed.

Precautions & Warnings

  • Abnormalities of hepatic, renal, haematological and other biochemical function tests
  • Hepatic necrosis
  • Exfoliative cutaneous reactions
  • Use during lactation
  • Driving/Use of machinery

Use in Special Populations

  • Elderly patients
  • Renal impairment

Overdose Effects

Supportive measures and symptomatic treatment with gastric lavage if necessary may be adequate.

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

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