Funga 150 mg (Capsule)
Unit Price: ৳ 18.00 (20's pack: ৳ 360.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Doctors chemical works ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol in fungal cell membrane
Dosage & Administration
- Different dosage for adults and children
- Oral and IV administration
- Special dosage for elderly patients
- Dosage modification for patients with renal impairment
- Use in specific population - children
Interaction
- Effect on prothrombin time with warfarin
- Co-administration with oral sulphonylureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin and rifampicin
- Effect on combined oral contraceptives
- Effect on cyclosporin concentrations
- Effect on absorption with food, cemetidine, antacids, and total body irradiation
- Effect on theophylline clearance
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely encountered rash
- Rare cases of anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals at high dose levels
- Not recommended in pregnancy or in women of childbearing potential
- Use in lactating mothers not recommended
Precautions & Warnings
- Observation of hepatic, renal, haematological, and biochemical function tests
- Risk of hepatic necrosis
- Rare development of severe cutaneous reactions
- Discontinuation of therapy in case of rash
- Not recommended during lactation
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Normal dose usage in elderly with no evidence of renal impairment
- Dose adjustment in patients with renal impairment
- Dosage modification according to creatinine clearance
Overdose Effects
- Supportive and symptomatic treatment
- Gastric lavage if necessary
- Forced volume diuresis for increased elimination rate
- Hemodialysis decreases plasma levels by approximately 50%
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat