Naz 0.3% (Ophthalmic Solution)

5 ml drop: ৳ 100.50

Medicine Details

Indications

  • Treatment of fungal corneal ulcers
  • Treatment of keratitis

Pharmacology

  • Fungistatic action
  • Inhibition of cytochrome P-450 14-α demethylase
  • Accumulation of lanosterol
  • Decreased concentration of ergosterol
  • Alteration of cellular membrane
  • Increased membrane permeability
  • Leakage of essential elements
  • Impaired uptake of precursor molecules to DNA

Dosage & Administration

  • Instill 1 drop into affected eye(s)
  • Five times daily

Interaction

  • Altering pharmacokinetics of certain drugs undergoing hepatic metabolism

Contraindications

  • Hypersensitivity to azoles

Side Effects

  • Generally well tolerated
  • Reported eosinophillia

Pregnancy & Lactation

  • Pregnancy category C
  • Use only if potential benefit justifies potential risk to fetus
  • Excretion in breast milk
  • Prohibition for nursing mothers

Precautions & Warnings

  • Overgrowth of non-susceptible strains of candida

Therapeutic Class

  • Ophthalmic Anti-fungal Products

Storage Conditions

  • Keep out of the reach of children
  • Store in a cool, dry place
  • Away from heat and direct light
  • Do not use more than 4 weeks after opening the bottle

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