Iconal 100 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Itraconazole |
| Company | Kemiko pharmaceuticals ltd |
Title
Iconal 100 mg Capsule
Categories
- Medicine
- Antifungal
- Pharmaceutical
Description
Iconal is used for the treatment of oropharyngeal candidiasis, vulvovaginal candidiasis, pityriasis versicolor, tinea pedis, tinea cruris, tinea corporis, tinea manuum, onychomycosis, histoplasmosis. It is indicated in the treatment of systemic candidiasis, aspergillosis, and cryptococcosis. It is also used for maintenance therapy in AIDS patients to prevent relapse of underlying fungal infections and in the prevention of fungal infection during prolonged neutropenia. It inhibits Cytochrome P-450 dependent enzymes and impairs the biosynthesis of ergosterol, a major component of the cell membrane of yeast and fungal cells.
Dosage
- 100 & 200 mg preparation:
- Non-systemic fungal disease:
- Vulvovaginal candidiasis: 200 mg twice daily for 1 day
- Pityriasis versicolor: 200 mg once daily for 7 days
- Tinea corporis, tinea cruris: 100 mg once daily for 15 days or 200 mg once daily for 7 days
- Systemic fungal disease:
- Aspergillosis: 200 mg once daily for 2-5 months
- Candidiasis: 100-200 mg once daily for 3 weeks-7 months
- Candidiasis: 200 mg twice daily for 2-6 months
- Non-systemic fungal disease:
- 65 mg & 130 mg preparation:
- Non-systemic fungal disease:
- Vulvovaginal candidiasis: 130 mg twice daily for 1 day
- Pityriasis versicolor: 65 mg once daily for 7 days
- Tinea corporis, tinea cruris: 65 mg once daily for 15 days
- Systemic fungal disease:
- Aspergillosis: 65 mg twice daily for 2-5 months
- Candidiasis: 65-130 mg once daily for 3 weeks-7 months
- Candidiasis: 130 mg twice daily for 2-6 months
- Non-systemic fungal disease:
Interaction
Avoid concurrent use with terfenadine, astemizole, cisapride, HMG-CoA reductase inhibitors, oral midazolam, triazolam, rifampin, phenytoin, phenobarbital, digoxin, and calcium channel blockers.
Contraindications
Contraindicated in patients with known hypersensitivity to the drug or any ingredient in the formulation. Not advised for patients with severe hepatic disease. Avoid use in patients taking rifampin.
Side Effects
- Nausea
- Abdominal pain
- Dyspepsia
- Constipation
- Headache
- Dizziness
- Raised liver enzymes
- Allergic reactions
- Hepatitis
- Cholestatic jaundice
- Peripheral neuropathy
- Stevens-Johnson syndrome
- Hypokalaemia
- Edema
- Hair loss
Pregnancy & Lactation
Contraindicated in pregnancy. Not recommended for breastfeeding.
Precautions & Warnings
Gastric acidity reduction impairs absorption. Administer after a full meal. Monitor liver function in patients receiving continuous treatment of more than one month.
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Store below 25°C, in a cool & dry place. Keep away from light. Keep out of reach of children.
Common Questions
- Iconal 100 mg Capsule helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Take Iconal 100 mg Capsule with food, at the same time every day.
- Use a reliable method of contraception to prevent pregnancy while taking Iconal 100 mg Capsule.
- Do not take indigestion remedies (antacids) within two hours of taking Iconal 100 mg Capsule.
- Your doctor may check your liver function before starting treatment and regularly thereafter.
- Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss.