Itra 100 mg (Capsule)
Unit Price: ৳ 15.10 (4 x 6: ৳ 362.40)
Strip Price: ৳ 90.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Itraconazole |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of oropharyngeal candidiasis
- Vulvovaginal candidiasis
- Pityriasis versicolor
- Tinea pedis
- Tinea cruris
- Tinea corporis
- Tinea manuum
- Onychomycosis
- Histoplasmosis
- Systemic candidiasis
- Aspergillosis
- Cryptococcosis
- Maintenance therapy in AIDS patients
- Prevention of fungal infection during prolonged neutropenia
Pharmacology
- Inhibits Cytochrome P-450 dependent enzymes
- Impairs biosynthesis of ergosterol
- Affects cell membrane of yeast and fungal cells
- Utilizes SUBA (Super Bio-available) technology for enhancing bioavailability of poorly soluble drugs
Dosage & Administration
- Available in 100 & 200 mg preparations
- Different dosages for non-systemic and systemic fungal diseases
- Specific dosages for different types of fungal diseases
- Pediatric use not established
Interaction
- Should not be given concurrently with terfenadine, astemizole, cisapride, HMG-CoA reductase inhibitors, oral midazolam or triazolam
- Significant interactions observed with rifampin, phenytoin, phenobarbital, digoxin, and calcium channel blockers
Contraindications
- Known hypersensitivity to the drug or any ingredient in the formulation
- Severe hepatic disease
- Contraindicated in patients taking rifampin
Side Effects
- Nausea
- Abdominal pain
- Dyspepsia
- Constipation
- Headache
- Dizziness
- Raised liver enzymes
- Menstrual disorders
- Allergic reactions
- Hepatitis and cholestatic jaundice
- Peripheral neuropathy
- Stevens-Johnson syndrome
- Hypokalaemia
- Oedema
- Hair loss
Pregnancy & Lactation
- Contraindicated in pregnancy
- Not recommended during breastfeeding
Precautions & Warnings
- Absorption is impaired when gastric acidity is reduced
- Administration with acid neutralizing medicines should be at least 2 hours apart
- Administered after a full meal
- Cases of hepatitis and jaundice reported in patients treated for longer than one month
- Liver function monitoring advised for continuous treatment of more than one month
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Store below 25°C
- Cool & dry place
- Keep away from light
- Keep out of the reach of children
Common Questions about Itra 100 mg Capsule
- Antifungal medication that inhibits Cytochrome P-450 dependent enzymes
- Used to treat fungal infections
- Duration of effect lasts up to 16 to 28 hours
- Peak effect observed at 2 hours
- Not habit forming
- Not recommended for breastfeeding women
Quick Tips
- Helps treat fungal infections of mouth, skin, vagina or any other parts of the body
- Do not skip any doses and finish the full course of treatment
- Take with food
- Use reliable contraception to prevent pregnancy while taking
- Do not take indigestion remedies (antacids) within two hours
- Liver function may be checked before starting treatment
- Inform doctor if allergic reactions, nerve pain, or hearing loss