Itracon 100 mg (Capsule)
Unit Price: ৳ 17.00 (3 x 10: ৳ 510.00)
Strip Price: ৳ 170.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Itraconazole |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Title
- Itracon 100 mg Capsule
Categories
- Antifungal Medication
- Pharmaceutical Products
- Medicine
- Healthcare
Description
- Inhibits Cytochrome P-450 dependent enzymes
- Treats fungal infections
- Enhances bioavailability of poorly soluble drugs
- Broad spectrum of activity
- Uses SUBA technology for improving drug dissolution
- Orally active triazole antifungal drug
Dosage & Administration
- 100 mg preparation
- 200 mg preparation
- 65 mg & 130 mg preparation
- Suitable duration as per the condition being treated
- Adjustable dosages as per clinical response
- Pediatric use is not established
Indications
- Used for oropharyngeal candidiasis
- Treats vulvovaginal candidiasis
- Effective against pityriasis versicolor
- Addresses various types of tinea infections
- Treatment for onychomycosis and histoplasmosis
- Indicated for systemic candidiasis, aspergillosis, and cryptococcosis
- Maintenance therapy in AIDS patients
Mode of Action
- Inhibition of Cytochrome P-450
- Impairment of ergosterol biosynthesis
- Membrane permeability abnormalities
- Abnormal cell wall formation
- Accumulation of intracellular lipids
Interaction
- Contraindicated with terfenadine, astemizole, cisapride
- Rifampin, phenytoin, phenobarbital interactions observed
- Concurrent use with HMG-CoA reductase inhibitors
- Caution with oral midazolam or triazolam
Contraindications
- Hypersensitivity to the drug or any ingredient in the formulation
- Severe hepatic disease
- Contraindicated in patients taking rifampin
Side Effects
- Nausea
- Abdominal pain
- Dyspepsia
- Headache
- Dizziness
- Raised liver enzymes
- Menstrual disorders
- Allergic reactions
- Hepatitis and cholestatic jaundice
- Peripheral neuropathy
- Stevens-Johnson syndrome
- Hypokalaemia
- Oedema
- Hair loss
Pregnancy & Lactation
- Contraindicated in pregnancy
- Not recommended during breastfeeding
Precautions & Warnings
- Impaired absorption with reduced gastric acidity
- Avoid concurrent use with acid neutralizing medicines
- Administer after a full meal
- Monitor liver function in patients on continuous treatment
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Store below 25°C
- Keep in a cool & dry place
- Keep away from light
- Keep out of reach of children
Common Questions
- Duration of effect: up to 16 to 28 hours
- Onset of action: observed at 2 hours
- Not habit-forming
- Use reliable contraception to prevent pregnancy
- Avoid indigestion remedies within two hours of intake