Sulfacetamide sodium

Generic Details

Generic Name

Sulfacetamide Sodium

Other Names

  • Sodium Sulfacetamide

Drug Class

  • Antibacterial

Chemical Formula

C8H9N2NaO3S

Molecular Weight

254.23 g/mol

Mechanism of Action

  • Inhibition of bacterial folate synthesis

Indications

  • Bacterial infections of the eye, skin, and urinary tract

Common Dosage Forms

  • Topical cream
  • Topical solution

Typical Dosage

  • Apply a thin layer to the affected area 1-3 times daily

Pediatric Dosage

  • Consult a healthcare provider for appropriate dosing

Geriatric Dosage

  • May require dosage adjustment; consult healthcare provider

Side Effects

  • Skin irritation
  • Stinging sensation
  • Redness at application site

Contraindications

  • Hypersensitivity to sulfonamides

Pregnancy Category

  • Category C - Consult healthcare provider before use

Lactation Safety

  • Considered safe with caution; consult healthcare provider

Drug Interactions

  • May interact with oral anticoagulants

Overdose Symptoms

  • Nausea
  • Vomiting
  • Confusion

Antidote for Overdose

  • Supportive care; no specific antidote

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Absorbed systemically after topical application
  • Distribution: Distributed widely in body tissues
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted renally

Precautions

  • Avoid contact with eyes
  • Not for internal use

Warnings

  • Discontinue use if signs of hypersensitivity develop

Others