Bambuterol Hydrochloride
Generic Details
Generic Name
Bambuterol Hydrochloride
Other Names
- Bambuterol HCl
Drug Class
- Bronchodilator
- Beta-2 Agonist
Chemical Formula
C18H29N3O4
Molecular Weight
347.44 g/mol
Mechanism of Action
- Selective β2-adrenergic agonist
- Prodrug of terbutaline
Indications
- Chronic obstructive pulmonary disease (COPD)
- Asthma
Common Dosage Forms
- Tablet
- Syrup
Typical Dosage
- 10-20 mg once daily
Pediatric Dosage
- Consult pediatrician for appropriate dosage
Geriatric Dosage
- Adjust dosage based on renal function
Side Effects
- Tremors
- Tachycardia
- Hypokalemia
- Headache
Contraindications
- Hypersensitivity to beta-adrenergic agonists
Pregnancy Category
- C - Risk cannot be ruled out
Lactation Safety
- Limited data, use caution
Drug Interactions
- Beta-blockers
- Diuretics
Overdose Symptoms
- Severe tremors
- Palpitations
- Hypotension
Antidote for Overdose
- Beta-blockers
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Well absorbed orally
- Distribution: Wide distribution in the body
- Metabolism: Metabolized in the liver
- Excretion: Primarily excreted in urine
Precautions
- Monitor potassium levels
- Caution in patients with cardiovascular disease
Warnings
- Not to be used as a rescue medication for acute bronchospasm