Testosterone Decanoate

Generic Details

Generic Name

Testosterone Decanoate

Other Names

  • Testosterone Deca
  • TD

Drug Class

  • Androgen
  • Anabolic Steroid

Chemical Formula

C29H46O3

Molecular Weight

442.707 g/mol

Mechanism of Action

  • Binds to androgen receptors
  • Promotes protein synthesis
  • Enhances muscle growth

Indications

  • Hypogonadism
  • Delayed puberty in males
  • Muscle wasting disorders

Common Dosage Forms

  • Injection

Typical Dosage

  • 200-400 mg every 2-4 weeks

Pediatric Dosage

  • Not established

Geriatric Dosage

  • Adjust dose based on individual response

Side Effects

  • Acne
  • Hair loss
  • Increased blood pressure
  • Liver toxicity
  • Mood changes

Contraindications

  • Prostate cancer
  • Breast cancer in males
  • Pregnancy

Pregnancy Category

  • X - Contraindicated

Lactation Safety

  • Not recommended

Drug Interactions

  • Warfarin
  • Insulin
  • Oral hypoglycemic agents

Overdose Symptoms

  • Virilization in females
  • Edema
  • Liver dysfunction

Antidote for Overdose

  • Supportive care

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Slow and sustained release from injection site
  • Distribution: Widely distributed in the body
  • Metabolism: Metabolized in the liver
  • Excretion: Mainly excreted in urine

Precautions

  • Monitor liver function
  • Monitor lipid levels
  • Monitor for virilization in females

Warnings

  • Increased risk of cardiovascular events
  • May cause benign prostatic hyperplasia

Others

  • Regular monitoring of hormonal levels is advised during therapy