Tetracycline Hydrochloride (Ophthalmic)

Generic Details

Generic Name

Tetracycline Hydrochloride Ophthalmic

Other Names

  • Tetracycline Eye Ointment
  • Tetracycline Eye Drops

Drug Class

  • Antibiotic

Chemical Formula

C22H24N2O8 · HCl

Molecular Weight

480.90 g/mol

Mechanism of Action

  • Inhibition of bacterial protein synthesis

Indications

  • Bacterial eye infections such as conjunctivitis, blepharitis, and keratitis

Common Dosage Forms

  • Ophthalmic ointment
  • Ophthalmic solution

Typical Dosage

  • Apply a small amount of ointment in the affected eye(s) 1-2 times daily

Pediatric Dosage

  • Use under the guidance of a healthcare provider

Geriatric Dosage

  • Adjust dosage based on individual patient requirements

Side Effects

  • Blurry vision
  • Eye irritation
  • Burning or stinging sensation in the eye

Contraindications

  • Hypersensitivity to tetracycline antibiotics

Pregnancy Category

  • Category D - Positive evidence of risk

Lactation Safety

  • Use caution; may excrete into breast milk

Drug Interactions

  • Interacts with antacids, calcium supplements, and iron-containing products

Overdose Symptoms

  • Severe eye irritation
  • Increased side effects

Antidote for Overdose

  • No specific antidote; symptomatic treatment

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Limited systemic absorption through the eyes
  • Distribution: Distributed to ocular tissues
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in urine and feces

Precautions

  • Avoid contact with contact lenses
  • Do not use in viral or fungal eye infections

Warnings

  • Discontinue use if irritation or allergic reaction occurs

Others

  • Consult a healthcare provider before use.