Beclomethasone Dipropionate (Inhaler)

Generic Details

Generic Name

Beclomethasone Dipropionate Inhaler

Other Names

  • Qvar
  • Becotide
  • Vanceril

Drug Class

  • Corticosteroid

Chemical Formula

C28H37ClO7

Molecular Weight

521.04 g/mol

Mechanism of Action

  • Anti-inflammatory effects by inhibiting the release of inflammatory mediators.

Indications

  • Asthma
  • Chronic obstructive pulmonary disease (COPD)

Common Dosage Forms

  • Inhaler

Typical Dosage

  • 100-200 mcg twice daily for asthma maintenance therapy

Pediatric Dosage

  • Children: 50-100 mcg twice daily

Geriatric Dosage

  • Use with caution, dosing may need adjustment based on individual factors.

Side Effects

  • Throat irritation
  • Hoarseness
  • Fungal infections in the mouth/throat
  • Increased risk of pneumonia

Contraindications

  • Hypersensitivity to beclomethasone or any components of the formulation

Pregnancy Category

  • C - Use with caution if benefits outweigh risks

Lactation Safety

  • Caution advised as it can pass into breast milk

Drug Interactions

  • Caution with strong CYP3A4 inhibitors (e.g., ritonavir) may increase systemic corticosteroid effects.

Overdose Symptoms

  • Nausea
  • Vomiting
  • Headache
  • Dizziness

Antidote for Overdose

  • Supportive care and monitoring

Storage Conditions

  • Store at controlled room temperature between 68°F to 77°F (20°C to 25°C). Protect from light.

Pharmacokinetics

  • Absorption: Rapidly absorbed from the lungs
  • Distribution: Mainly to the lungs
  • Metabolism: Hepatic metabolism
  • Excretion: Primarily eliminated in the feces

Precautions

  • Monitor for signs of adrenal insufficiency with long-term use
  • Gradually taper doses when discontinuing therapy to prevent adrenal crisis

Warnings

  • Not for acute asthma attacks, requires regular daily use for optimal effect

Others

  • Always rinse mouth after inhalation to reduce the risk of oral fungal infections.