Zinc Sulfate Monohydrate

Generic Details

Generic Name

Zinc Sulfate Monohydrate

Other Names

  • Zinc Sulfate Hydrate

Drug Class

  • Mineral supplement

Chemical Formula

ZnSO4.H2O

Molecular Weight

179.47 g/mol

Mechanism of Action

  • Zinc is essential for the activity of over 300 enzymes involved in various biochemical pathways in the body.

Indications

  • Zinc deficiency
  • Skin conditions like acne
  • Wound healing
  • Immune support

Common Dosage Forms

  • Tablet
  • Capsule
  • Liquid
  • Lozenge

Typical Dosage

  • 15-30 mg elemental zinc per day

Pediatric Dosage

  • Consult pediatrician for appropriate dosage

Geriatric Dosage

  • May require lower doses due to reduced kidney function

Side Effects

  • Nausea
  • Vomiting
  • Metallic taste in the mouth
  • Stomach upset

Contraindications

  • Hypersensitivity to zinc
  • Chronic kidney disease

Pregnancy Category

  • A - Studies have shown no risk to the fetus

Lactation Safety

  • Compatible with breastfeeding

Drug Interactions

  • Antibiotics like tetracycline and quinolones may have reduced absorption when taken with zinc supplements

Overdose Symptoms

  • Nausea
  • Vomiting
  • Epigastric pain
  • Fatigue
  • Headache

Antidote for Overdose

  • Gastric lavage or symptomatic treatment

Storage Conditions

  • Store at room temperature in a dry place

Pharmacokinetics

  • Absorption: Primarily in the small intestine
  • Distribution: Distributed mainly in the liver, kidneys, and muscles
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in urine and feces

Precautions

  • Monitor zinc levels regularly to prevent toxicity

Warnings

  • Avoid taking zinc supplements with high-fiber foods or beverages as they may reduce zinc absorption

Others