Betamethasone + Neomycin Sulphate (Topical)
Generic Details
Generic Name
Betamethasone-Neomycin Sulphate Topical
Other Names
- Betamethasone-Neomycin Cream
Drug Class
- Topical corticosteroid and antibiotic combination
Chemical Formula
Molecular Weight
Mechanism of Action
- Betamethasone: corticosteroid that reduces itching, redness, and swelling. Neomycin: antibiotic that treats or prevents bacterial infections.
Indications
- Skin inflammation
- Eczema
- Dermatitis
- Allergic reactions
- Insect bites
Common Dosage Forms
- Cream
- Ointment
Typical Dosage
- Apply a thin layer to the affected area 2-4 times daily
Pediatric Dosage
- Use with caution and follow pediatrician's advice
Geriatric Dosage
- May require dosage adjustment based on individual factors, consult healthcare provider
Side Effects
- Skin irritation
- Burning
- Itching
- Allergic reactions
- Skin thinning with prolonged use
Contraindications
- Hypersensitivity to betamethasone or neomycin
- Skin infections caused by viruses or fungi
Pregnancy Category
- C - Use with caution if benefits outweigh risks
Lactation Safety
- Use with caution, consult healthcare provider
Drug Interactions
- No significant interactions reported
Overdose Symptoms
- Unlikely with topical use, systemic effects when applied excessively over large areas
Antidote for Overdose
- None, contact a healthcare provider if suspected overdose
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Limited systemic absorption with topical application
- Distribution: Not well studied, expected minimal distribution to systemic circulation
- Metabolism: Hepatic metabolism for systemic exposure
- Excretion: Primarily renal excretion
Precautions
- Avoid prolonged use on large areas of skin
- Not for use on broken or infected skin
Warnings
- Discontinue if skin irritation or allergic reaction occurs
- Avoid contact with eyes and mucous membranes