Salbutamol
Generic Details
Generic Name
Salbutamol
Other Names
- Albuterol
Drug Class
- Beta2-adrenergic agonist
Chemical Formula
C13H21NO3
Molecular Weight
239.31 g/mol
Mechanism of Action
- Selective agonist at beta2-adrenergic receptors resulting in bronchodilation
Indications
- Asthma
- Chronic obstructive pulmonary disease (COPD)
- Exercise-induced bronchospasm
Common Dosage Forms
- Inhaler
- Nebulizer solution
- Tablet
- Syrup
Typical Dosage
- Inhaler: 90mcg per actuation, 2 puffs every 4-6 hours as needed
Pediatric Dosage
- Dosing based on weight and age, consult healthcare provider
Geriatric Dosage
- Dosage adjustment may be needed, consult healthcare provider
Side Effects
- Tachycardia
- Tremor
- Headache
- Nervousness
- Hypokalemia
Contraindications
- Hypersensitivity to Salbutamol
- Severe heart disease
Pregnancy Category
- C
Lactation Safety
- Compatible but monitor infant for side effects
Drug Interactions
- Beta-blockers
- Diuretics
- Monoamine oxidase inhibitors
Overdose Symptoms
- Palpitations
- Tachycardia
- Tremor
- Hypokalemia
Antidote for Overdose
- Beta-blockers
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Rapidly absorbed from the respiratory tract
- Distribution: Widely distributed in the body
- Metabolism: Primarily hepatic
- Excretion: Mainly renal
Precautions
- Use with caution in patients with cardiovascular disorders
Warnings
- Do not exceed recommended dose
- Seek medical help if symptoms worsen
Others
- Available as a rescue inhaler for acute symptoms