L-Ornithine L-Aspartate + Pancreatin
Generic Details
Generic Name
L-Ornithine-L-Aspartate-Pancreatin
Other Names
- LOLA-P
Drug Class
- Hepatoprotective agent
- Digestive enzyme
Chemical Formula
Molecular Weight
Mechanism of Action
- L-Ornithine-L-Aspartate helps in detoxification of ammonia in the liver
- Pancreatin aids in the digestion of fats, proteins, and carbohydrates
Indications
- Hepatic encephalopathy
- Chronic liver diseases
- Pancreatic insufficiency
Common Dosage Forms
- Tablet
- Powder for oral suspension
Typical Dosage
- 2-4 tablets per day
- Or as directed by a healthcare provider
Pediatric Dosage
- Consult a pediatrician for appropriate dosage
Geriatric Dosage
- Dose adjustment may be needed, consult a healthcare provider
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhea
- Allergic reactions
Contraindications
- Hypersensitivity to any component
- Severe liver or kidney disease
Pregnancy Category
- Consult healthcare provider
Lactation Safety
- Consult healthcare provider
Drug Interactions
- Antacids
- Proton pump inhibitors
- Warfarin
Overdose Symptoms
- Nausea
- Vomiting
- Abdominal pain
Antidote for Overdose
- Supportive care
Storage Conditions
- Store in a cool, dry place away from direct sunlight
Pharmacokinetics
- Absorption: Varies depending on the component
- Distribution: Not well defined
- Metabolism: Metabolized in the liver
- Excretion: Mainly through the urine
Precautions
- Monitor liver function regularly during therapy
- Caution in patients with known allergies
Warnings
- Discontinue if severe allergic reactions occur
- Not a substitute for a balanced diet
Others
- Avoid alcohol consumption while on therapy
- May interact with certain medications, consult a healthcare provider for guidance