Fluticasone Propionate (Topical)
Generic Details
Generic Name
Fluticasone Propionate Topical
Other Names
- Fluticasone Cream
- Fluticasone Ointment
Drug Class
- Topical Corticosteroid
Chemical Formula
C25H31F3O5S
Molecular Weight
500.6 g/mol
Mechanism of Action
- Anti-inflammatory
- Immunosuppressant
Indications
- Eczema
- Dermatitis
- Psoriasis
- Allergic Reactions
- Itching
Common Dosage Forms
- Cream
- Ointment
Typical Dosage
- Apply a thin layer to the affected area once or twice daily
Pediatric Dosage
- Consult healthcare provider for appropriate dosage
Geriatric Dosage
- May require lower doses, consult healthcare provider
Side Effects
- Skin irritation
- Burning
- Itching
- Dryness
- Acne
- Skin discoloration
Contraindications
- Hypersensitivity to corticosteroids
- Untreated skin infections
Pregnancy Category
- Category C - Consult healthcare provider
Lactation Safety
- Limited data available, consult healthcare provider
Drug Interactions
- No significant interactions reported with topical use
Overdose Symptoms
- Unlikely with topical application
Antidote for Overdose
- Not applicable for topical overdose
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Minimal systemic absorption through intact skin
- Distribution: Not well studied in topical form
- Metabolism: Hepatic metabolism
- Excretion: Mainly excreted in the feces
Precautions
- Avoid contact with eyes
- Do not use on open wounds
- Discontinue if skin irritation occurs
Warnings
- Not for ophthalmic use
- Do not exceed recommended dosage
Others
- It is important to follow the healthcare provider's instructions for proper use.