Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate
Generic Details
Generic Name
Sodium Alginate-Sodium Bicarbonate-Calcium Carbonate
Other Names
- Gaviscon
- Maalox
- Mylanta
Drug Class
- Antacid
- Reflux suppressant
Chemical Formula
Molecular Weight
Mechanism of Action
- Sodium alginate forms a gel-like layer on top of the stomach contents, preventing reflux.
- Sodium bicarbonate and calcium carbonate are antacids that neutralize stomach acid.
Indications
- Heartburn
- Acid indigestion
- Gastric reflux
Common Dosage Forms
- Chewable tablets
- Liquid suspension
Typical Dosage
- Chew 2-4 tablets after meals and at bedtime
- Take 5-10 ml of suspension after meals and at bedtime
Pediatric Dosage
- Dosage may vary based on weight and age - consult a pediatrician
Geriatric Dosage
- Lower doses may be required due to decreased kidney function
Side Effects
- Constipation
- Diarrhea
- Nausea
Contraindications
- Hypersensitivity to any component
- Kidney disease
Pregnancy Category
- Consult healthcare provider
Lactation Safety
- Consider risk vs. benefit
Drug Interactions
- Tetracyclines
- Digoxin
- Iron supplements - separate administration by 2 hours
Overdose Symptoms
- Alkalosis
- Hypocalcemia
Antidote for Overdose
- Supportive care
- Calcium gluconate for severe hypocalcemia
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Sodium bicarbonate is rapidly absorbed; calcium carbonate absorption is influenced by gastric acid.
- Distribution: Calcium is distributed mainly in bones and teeth.
- Metabolism: No significant metabolism.
- Excretion: Excreted primarily in the urine.
Precautions
- Renal impairment
- Avoid in patients with electrolyte disturbances
Warnings
- Do not take more than the recommended dose
- Consult a doctor if symptoms persist for more than 2 weeks
Others
- May interfere with the absorption of certain medications