Guaifenesin + Levomenthol + Diphenhydramine
Generic Details
Generic Name
Guaifenesin-Levomenthol-Diphenhydramine
Other Names
Drug Class
- Expectorant
- Cough Suppressant
- Antihistamine
Chemical Formula
Molecular Weight
Mechanism of Action
- Guaifenesin: Expectorant - increases respiratory tract fluid secretion and helps to loosen mucus in the airways.
- Levomenthol: Topical cooling sensation that can relieve nasal congestion and soothe the throat.
- Diphenhydramine: Antihistamine - blocks histamine, reducing symptoms of allergies and cough.
Indications
- Cough
- Chest congestion
- Runny nose
- Sneezing
- Allergies
Common Dosage Forms
- Syrup
- Tablet
Typical Dosage
- Adults: 1-2 tablets every 4-6 hours
- Children: Consult a healthcare provider for appropriate dosage
Pediatric Dosage
Geriatric Dosage
Side Effects
- Drowsiness
- Dry mouth
- Nausea
- Headache
- Dizziness
Contraindications
- Hypersensitivity to any component
- Asthma
- Glaucoma
- Severe liver or kidney disease
Pregnancy Category
- Category C - Consult healthcare provider before use
Lactation Safety
- Use with caution, excretion in breast milk is unknown
Drug Interactions
- MAO inhibitors
- Sedatives
- Alcohol
Overdose Symptoms
- Confusion
- Convulsions
- Hallucinations
Antidote for Overdose
- Activated charcoal
- Symptomatic treatment
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Varies
- Distribution: Crosses the placenta and enters breast milk
- Metabolism: Hepatic
- Excretion: Renal
Precautions
- Use with caution in elderly patients
- Avoid driving or operating machinery while on medication
Warnings
- May cause drowsiness, alcohol intensifies this effect
- Do not exceed recommended dosage